TABLE 30-4
Membrane-Bound Receptor Hormone Transduction Systems
Hormones acting via
utilization of a cAMP system
cAMP decrease
cAMP increase
Hormones acting via
a cGMP system
Hormones acting via
IP3 pathway
Hormones acting via
ion channels
Bradykinin
A
ATH
Atrial natriuretic
ACTH
Acetylcholine
Norepinephrine(ot
2
-adrenergic)
a-MSH
hormone
Angiotensin II/III
Nicotinic receptor
Somatostatin
Calcitonin
Cholecystokinin
(Na+ channel)
FSH
EGF
Nitric oxide (NO)
Gastrin
Epinephrine
(Ca2+ channel)
Glucagon
GnRH
GnRH
Histamine (HI)
Histamine (H2)
NGF
LH
Norepinephrine
Norepinephrine!/3, adreneigic)
(a, adrenergic)
PGEj
PGF
PTH
Thromboxanes
Secretin
TRH
TSH
TSH
Vasopressin
Vasopressin
VIP
VIP
Reprinted with permission from A. W. Norman and G. Litwack,
H orm ones
2nd ed.
Academic Press 1997, page 32.